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N 6-methyladenosine-modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing

Abstract Background The RNA N 6-methyladenosine (m6A) modification has become an essential hotspot in epigenetic modulation. Serine–arginine protein kinase 1 (SRPK1) is associated with the pathogenesis of various cancers. However, the m6A modification of SRPK1 and its association with the mechanism...

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主要な著者: Anqi Wang, Yuanyuan Zeng, Weijie Zhang, Jian Zhao, Lirong Gao, Jianjun Li, Jianjie Zhu, Zeyi Liu, Jian-an Huang
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2024-08-01
シリーズ:Cellular & Molecular Biology Letters
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オンライン・アクセス:https://doi.org/10.1186/s11658-024-00622-5
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