A novel TRIM22 gene polymorphism promotes the response to PegIFNα therapy through cytokine-cytokine receptor interaction signaling pathway in chronic hepatitis B

ABSTRACT Objectives: Pegylated interferon alfa (PegIFNα) has limited efficacy in patients with chronic hepatitis B (CHB). Because single-nucleotide polymorphisms (SNPs) are known to confer disease susceptibility and influence treatment response, we aimed to identify novel tripartite motif-containing...

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Autors principals:	Long Wang, Ni Lin, Yanfang Zhang, Shaoying Guo, Can Liu, Caorui Lin, Yongbin Zeng, Wennan Wu, Jianhui Guo, Chenggong Zhu, Fuguo Zhan, Qishui Ou, Zhen Xun
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2023-12-01
Col·lecció:	Microbiology Spectrum
Matèries:	tripartite motif-containing 22 chronic hepatitis B pegylated interferon alfa single-nucleotide polymorphism
Accés en línia:	https://journals.asm.org/doi/10.1128/spectrum.02247-23
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