Comparative Analysis of Clinical and Environmental Strains of Exophiala spinifera by Long-Reads Sequencing and RNAseq Reveal Adaptive Strategies

Exophiala spinifera, a capsule-producing black yeast, is overrepresented as agent of disseminated infection in humans with inherited dysfunction of the CARD9 gene. In a review of published caspase recruitment domain-containing protein 9 (CARD9) deficiency cases, black fungi were linked to mutations...

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Bibliographic Details

Main Authors:	Yinggai Song, Minghao Du, Nickolas Menezes da Silva, Ence Yang, Vania A. Vicente, G. Sybren de Hoog, Ruoyu Li
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Microbiology
Subjects:	black yeasts comparative genomics transcriptome analysis intraspecific variability gene rearrangement CARD9 deficiency
Online Access:	https://www.frontiersin.org/article/10.3389/fmicb.2020.01880/full
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