Citrullination and PAD Enzyme Biology in Type 1 Diabetes – Regulators of Inflammation, Autoimmunity, and Pathology

The generation of post-translational modifications (PTMs) in human proteins is a physiological process leading to structural and immunologic variety in proteins, with potentially altered biological functions. PTMs often arise through normal responses to cellular stress, including general oxidative c...

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Hlavní autoři:	Mei-Ling Yang, Fernanda M. C. Sodré, Mark J. Mamula, Lut Overbergh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-06-01
Edice:	Frontiers in Immunology
Témata:	type 1 diabetes neoepitopes post-translational modification citrullination peptidylarginine deiminase
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.678953/full
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