The Coup-TFII orphan nuclear receptor is an activator of the γ-globin gene
The human fetal γ-globin gene is repressed in the adult stage through complex regulatory mechanisms involving transcription factors and epigenetic modifiers. Reversing γ-globin repression, or maintaining its expression by manipulating regulatory mechanisms, has become a major clinical goal in the t...
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| Principais autores: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2020-02-01
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| coleção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/9675 |
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