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Implications of dimeric activation of PDE6 for rod phototransduction

We examine the implications of a recent report providing evidence that two transducins must bind to the rod phosphodiesterase to elicit significant hydrolytic activity. To predict the rod photoreceptor's electrical response, we use numerical simulation of the two-dimensional diffusional contact of i...

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Váldodahkkit: Trevor D. Lamb, Martin Heck, Timothy W. Kraft
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: The Royal Society 2018-08-01
Ráidu:Open Biology
Fáttát:
Liŋkkat:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180076
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