Plumbagin: A Promising In Vivo Antiparasitic Candidate against <i>Schistosoma mansoni</i> and In Silico Pharmacokinetic Properties (ADMET)

Schistosomiasis, a potentially fatal chronic disease whose etiological agents are blood trematode worms of the genus <i>Schistosoma</i> spp., is one of the most prevalent and debilitating neglected diseases. The treatment of schistosomiasis depends exclusively on praziquantel (PZQ), a drug that has...

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Päätekijät:	Lucas M. N. Silva, Wilza W. M. França, Victor H. B. Santos, Renan A. F. Souza, Adriana M. Silva, Emily G. M. Diniz, Thierry W. A. Aguiar, João V. R. Rocha, Mary A. A. Souza, Wheverton R. C. Nascimento, Reginaldo G. Lima Neto, Iranildo J. Cruz Filho, Eulália C. P. A. Ximenes, Hallysson D. A. Araújo, André L. Aires, Mônica C. P. A. Albuquerque
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2023-08-01
Sarja:	Biomedicines
Aiheet:	naphthoquinone plumbagin schistosomicidal in vivo assay <i>Schistosoma mansoni</i> histopathology
Linkit:	https://www.mdpi.com/2227-9059/11/9/2340
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