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Preparation and characterization of a iRGD-modified recombinant spider silk particles for antitumor polypeptide drug delivery into cancer cells

Abstract Spider silk is highly attractive material because of its superior mechanical properties and excellent biocompatibility, enabling it to self-assemble into a wide range of morphological structures for drug delivery system. However, most spider silk particles developed as drug carriers are bas...

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Principais autores: Ben Wang, Hongbo Li, Ying Chen, Zhi Chen, Pingping Li, Xi Zhang, Xiaoji Lin
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-08-01
Serier:BMC Biotechnology
Fag:
Spider silk particle
iRGD
Antitumor polypeptide
Drug delivery
Controlled release
Online adgang:https://doi.org/10.1186/s12896-025-01023-y
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