Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2

Eosinophils are key regulators of adipose tissue homeostasis, thus characterization of adipose tissue-related molecular factors capable of regulating eosinophil activity is of great interest. Leptin is known to directly activate eosinophils in vitro, but leptin ability of inducing in vivo eosinophil...

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Autors principals:	Natália R. T. Amorim, Glaucia Souza-Almeida, Tatiana Luna-Gomes, Patricia T. Bozza, Claudio Canetti, Bruno L. Diaz, Clarissa M. Maya-Monteiro, Christianne Bandeira-Melo
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-09-01
Col·lecció:	Frontiers in Endocrinology
Matèries:	eosinophils mast cells lipid droplets leptin prostaglandin D2 leukotriene C4
Accés en línia:	https://www.frontiersin.org/article/10.3389/fendo.2020.572113/full
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