The shape of human squalene epoxidase expands the arsenal against cancer
Abstract Squalene epoxidase (also known as squalene monooxygenase, EC 1.14.99.7) is a key rate-limiting enzyme in cholesterol biosynthesis. Anil Padyana and colleagues report the long awaited structure of human squalene epoxidase (SQLE). They solved the crystal structure of the catalytic domain of h...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Portfolio
2019-02-01
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| シリーズ: | Nature Communications |
| オンライン･アクセス: | https://doi.org/10.1038/s41467-019-08866-y |
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