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Targeting NLRP3 signaling reduces myocarditis-induced arrhythmogenesis and cardiac remodeling

Abstract Background Myocarditis substantially increases the risk of ventricular arrhythmia. Approximately 30% of all ventricular arrhythmia cases in patients with myocarditis originate from the right ventricular outflow tract (RVOT). However, the role of NLRP3 signaling in RVOT arrhythmogenesis rema...

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Principais autores: Chye-Gen Chin, Yao-Chang Chen, Fong-Jhih Lin, Yung-Kuo Lin, Yen-Yu Lu, Tzu-Yu Cheng, Shih-Ann Chen, Yi-Jen Chen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-04-01
Serier:Journal of Biomedical Science
Fag:
Myocarditis
NLRP3
Ventricular tachycardia
Right ventricular outflow tract
Online adgang:https://doi.org/10.1186/s12929-024-01032-7
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