Message and protein-level elevation of tumor necrosis factor α (TNFα) and TNFα-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis

Recent data indicate that certain pro-inflammatory cytokines are transcriptionally upregulated in the spinal cords of G93A-SOD1 mice, a model of amyotrophic lateral sclerosis (ALS). We previously showed that the receptor for tumor necrosis factor α (TNF-R1) was notably elevated at late presymptomati...

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Bibliografiska uppgifter

Huvudupphov:	Kenneth Hensley, Joe Fedynyshyn, Scott Ferrell, Robert A Floyd, Brian Gordon, Paula Grammas, Ladan Hamdheydari, Molina Mhatre, Shenyun Mou, Quentin N Pye, Charles Stewart, Melinda West, Stuart West, Kelly S Williamson
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2003-10-01
Serie:	Neurobiology of Disease
Ämnen:	Microglia Amyotrophic lateral sclerosis Neuroinflammation Tumor necrosis factor Cytokines Chemokines
Länkar:	http://www.sciencedirect.com/science/article/pii/S0969996103000871
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