Interleukin-17A influences the vulnerability rather than the size of established atherosclerotic plaques in apolipoprotein E-deficient mice

Interleukin (IL)-17A plays a role in the development of atherosclerotic plaques; however, the mechanism remains unclear. In this study, apolipoprotein E-deficient (ApoE–/–) mice were fed a high-fat diet to induce atherosclerosis, followed by the treatment with exogenous recombinant IL-17A or the neu...

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Detalhes bibliográficos

Principais autores:	Wang Bo, Hou Xitan, Sun Yaning, Lei Chao, Yang Sha, Zhu Yao, Jiang Yingming, Song Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	De Gruyter 2022-09-01
coleção:	Open Life Sciences
Assuntos:	il-17a il-17 neutralizing antibody atherosclerosis plaque vulnerability macrophage efferocytosis
Acesso em linha:	https://doi.org/10.1515/biol-2022-0072
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