Enhancement of lentiviral vectors gene delivery against VEGFR2 expressing cells by co-display of the binding and fusogenic moieties: a two molecules targeting approach

Abstract Background Pseudotyped lentiviral vectors (LVs) were used in cancer therapy as gene delivery systems for inhibiting tumor angiogenesis by targeting cells overexpressing “vascular endothelial growth factor receptor-2 (VEGFR2)”. Herein, we report that switching from chimeric sindbis virus gly...

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Huvudupphov:	Roshanak Ahani, Mohammad Hossein Etemadzadeh, Nasir Mohajel, Mahdi Behdani, Reza Ahangari Cohan, Mohamad Reza Kalani, Navid Madani, Farzin Roohvand, Kayhan Azadmanesh
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2025-09-01
Serie:	Virology Journal
Länkar:	https://doi.org/10.1186/s12985-025-02923-3
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