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Factors defining the functional oligomeric state of Escherichia coli DegP protease.

Escherichia coli DegP protein is a periplasmic protein that functions both as a protease and as a chaperone. In the absence of substrate, DegP oligomerizes as a hexameric cage but in its presence DegP reorganizes into 12 and 24-mer cages with large chambers that house the substrate for degradation o...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Jack Iwanczyk, Vivian Leong, Joaquin Ortega
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-04-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3081313?pdf=render
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