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Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes

There is a need for countermeasures to mitigate lethal acute radiation syndrome (ARS) and delayed effects of acute radiation exposure (DEARE). In WAG/RijCmcr rats, ARS occurs by 30-days following total body irradiation (TBI), and manifests as potentially lethal gastrointestinal (GI) and hematopoieti...

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Principais autores: Tracy Gasperetti, Tessa Miller, Feng Gao, Jayashree Narayanan, Elizabeth R. Jacobs, Aniko Szabo, George N. Cox, Christie M. Orschell, Brian L. Fish, Meetha Medhora
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021-05-01
Serija:Frontiers in Pharmacology
Teme:
polypharmacy
acute radiation syndrome
delayed effects of acute radiation exposure
mitigation
hematopoietic growth factor
lisinopril
Online dostop:https://www.frontiersin.org/articles/10.3389/fphar.2021.634477/full
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