BMP and NODAL paracrine signalling regulate the totipotent-like cell state in embryonic stem cells

Cell–cell communication coordinates signalling between cells to guide context-dependent cell fate decisions such as proliferation, differentiation, and lineage specification. Such communication mechanisms are poorly understood in regulating the stem cell states. In this study, we investigate how cel...

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Detalhes bibliográficos

Principais autores:	Sanidhya Jagdish, Loick Joumier, Sabin Dhakal, Gilberto Duran-Bishop, Mohammed Usama, Mohan Malleshaiah
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	bone morphonegentic protein (BMP) Signalling embryonic stem cells nodal signalling paracrine signalling totipotent-like cell state
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1720355/full
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