UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling

Emerging evidence has demonstrated that ubiquitin conjugating enzyme E2 J1 (UBE2J1) exerts pivotal function in many cancers. UBE2J1 was reported to be dysregulated in endometrial cancer (EC). This study was designed to further investigate the regulatory character and mechanism of UBE2J1 in EC. Bioin...

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Principais autores:	Zhang Ping, Guo Huiping, Zhao Fang, Jia Ke, Yang Fei, Liu Xiaoli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	De Gruyter 2023-02-01
coleção:	Open Medicine
Assuntos:	cell apoptosis endometrial cancer mdm2/p53 pathway pi3k/akt pathway ube2j1
Acesso em linha:	https://doi.org/10.1515/med-2022-0567
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