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Coupled small molecules target RNA interference and JAK/STAT signaling to reduce Zika virus infection in Aedes aegypti.

The recent global Zika epidemics have revealed the significant threat that mosquito-borne viruses pose. There are currently no effective vaccines or prophylactics to prevent Zika virus (ZIKV) infection. Limiting exposure to infected mosquitoes is the best way to reduce disease incidence. Recent stud...

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Principais autores: Chasity E Trammell, Gabriela Ramirez, Irma Sanchez-Vargas, Laura A St Clair, Oshani C Ratnayake, Shirley Luckhart, Rushika Perera, Alan G Goodman
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Pathogens
Acceso en liña:https://doi.org/10.1371/journal.ppat.1010411
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