Breaking the medication overuse headache cycle: from nociplastic pain mechanisms to patient-centered interventions — the Junior Editorial Board vision

Abstract Background Medication-overuse headache (MOH) is a prevalent and disabling secondary headache disorder that arises in individuals with a pre-existing primary headache as a consequence of regular overuse of acute medications. Increasing evidence suggests that MOH shares fundamental pathophysi...

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Principais autores:	Roberta Messina, Matteo Castaldo, Woo-Seok Ha, Alejandro Labastida-Ramirez, Sophie Merve Yener, Agnese Onofri, Eloisa Rubio-Beltran, Gabriele Sebastianelli, Doga Vuralli, William Wells-Gatnik, Paolo Martelletti
格式:	Artigo
语言:	Inglês
出版:	BMC 2026-04-01
丛编:	The Journal of Headache and Pain
主题:	Medication-overuse headache Nociplastic pain Central sensitization CGRP-targeting therapies Behavioural interventions Withdrawal
在线阅读:	https://doi.org/10.1186/s10194-026-02358-3
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