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ThPOK Inhibits Osteoclast Formation Via NFATc1 Transcription and Function

ABSTRACT Both LRF (Zbtb7a) and ThPOK (Zbtb7b) belong to the POK (BTB/POZ and Kruppel) family of transcription repressors that participate in development, differentiation, and oncogenesis. Although LRF mediates osteoclast differentiation by regulating NFATc1 expression, the principal established func...

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Autori principali: Wei Zou, Takashi Izawa, Nidhi Rohatgi, Steven Y Zou, Yongjia Li, Steven L Teitelbaum
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2022-04-01
Serie:JBMR Plus
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Accesso online:https://doi.org/10.1002/jbm4.10613
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