Unleashing CAR-T potential in solid tumors: overcoming intrinsic and extrinsic hurdles to improve therapy
Abstract Chimeric antigen receptor (CAR) T cell therapy has shown transformative success in hematologic malignancies, yet its application in solid tumors remains limited by a combination of intrinsic and extrinsic barriers. Intrinsically, CAR-T cells face challenges such as CAR instability, T cell e...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer
2026-01-01
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| Reeks: | Cancer Immunology, Immunotherapy |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.1007/s00262-025-04278-8 |
| Tags: |
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