Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD.
Long-term depression (LTD) is a long-lasting activity-dependent decrease in synaptic strength. NMDA receptor (NMDAR)-dependent LTD, an extensively studied form of LTD, involves the endocytosis of AMPA receptors (AMPARs) via protein dephosphorylation, but the underlying mechanism has remained unclear...
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| Autori principali: | , , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2009-09-01
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| Serie: | PLoS Biology |
| Accesso online: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000187&type=printable |
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