Diameter dependence of transport through nuclear pore complex mimics studied using optical nanopores

The nuclear pore complex (NPC) regulates the selective transport of large biomolecules through the nuclear envelope. As a model system for nuclear transport, we construct NPC mimics by functionalizing the pore walls of freestanding palladium zero-mode waveguides with the FG-nucleoporin Nsp1. This ap...

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Podrobná bibliografie

Hlavní autoři:	Nils Klughammer, Anders Barth, Maurice Dekker, Alessio Fragasso, Patrick R Onck, Cees Dekker
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2024-02-01
Edice:	eLife
Témata:	nuclear pore complex solid-state nanopores nucleocytoplasmic transport single-molecule fluorescence biomimetics intrinsically disordered proteins
On-line přístup:	https://elifesciences.org/articles/87174
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