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Exploring Tafamidis Effects Through PBPK–QSP Modelling

<b>Background/Objectives</b>: Tafamidis, a transthyretin kinetic stabilizer, increases circulating transthyretin levels in treated patients. While this effect is well documented, its underlying mechanism remains incompletely understood. This study aimed to evaluate the performance of physiologically...

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Bibliographic Details
Main Authors: Seweryn Ulaszek, Bartek Lisowski, Barbara Wiśniowska, Sebastian Polak
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-03-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/18/3/367
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