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Inner Ear Delivery of Polyamino Acid Nanohydrogels Loaded with Dexamethasone

ObjectiveTo develop a novel polyamino acid-based nanohydrogel drug delivery system for dexamethasone to enhance its delivery efficiency to the inner ear.MethodsA fluorescein-labeled polyglutamic acid-based polyamino acid dexamethasone nanohydrogel was synthesized, and its gelation time was measured....

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Principais autores: AI Pingping, ZHAO Lidong, TANG Zhaohui, HE Chaoliang, CHEN Xuesi, YANG Shiming, WU Nan
Format: Artigo
Sprog:Chinês
Udgivet: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2025-02-01
Serier:Xiehe Yixue Zazhi
Fag:
polyamino acid
nanohydrogel
dexamethasone
otology
pharmacokinetics
Online adgang:https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0455
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