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Methods for Preclinical Assessment of the Efficacy of Anticancer Medicines <i>in vivo</i> (Review)

INTRODUCTION. The main risk to the clinical translatability of preclinical results for anticancer medicinal products is posed by the difficulty of simulating clinical conditions in an experimental model. With only 5% of product candidates proving clinically effective, the search for new approaches t...

Ausführliche Beschreibung

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Hauptverfasser: M. L. Vasyutina, K. V. Lepik, M. S. Istomina, K. A. Levchuk, A. V. Petukhov, E. V. Shchelina, A. E. Ershova, O. N. Demidov, Ya. G. Toropova
Format: Artigo
Sprache:Russo
Veröffentlicht: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2025-07-01
Schriftenreihe:Регуляторные исследования и экспертиза лекарственных средств
Schlagworte:
ксенографтные модели
ксенотрансплантат
<i>in vivo</i> визуализация
противоопухолевая активность
модели рака на животных
доклинические исследования
Online-Zugang:https://www.vedomostincesmp.ru/jour/article/view/655
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