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Contributions of histone H3 nucleosome core surface mutations to chromatin structures, silencing and DNA repair.

Histone H3 mutations in residues that cluster in a discrete region on the nucleosome surface around lysine 79 of H3 affect H3-K79 methylation, impair transcriptional silencing in subtelomeric chromatin, and reveal distinct contributions of histone H3 to various DNA-damage response and repair pathway...

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Bibliografiske detaljer
Principais autores: Michel Fink, Jeffrey S Thompson, Fritz Thoma
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-01-01
Serier:PLoS ONE
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22053185/pdf/?tool=EBI
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