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Integrative analysis in head and neck cancer reveals distinct role of miRNome and methylome as tumour epigenetic drivers

Abstract Head and neck cancer is the sixth most common malignancy worldwide, with the relatively low 5-year survival rate, mainly because it is diagnosed at a late stage. Infection with HPV is a well known aetiology, which affects the nature of these cancers and patients’ survival. Besides, it is co...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Katarina Mandić, Nina Milutin Gašperov, Ksenija Božinović, Emil Dediol, Jure Krasić, Nino Sinčić, Magdalena Grce, Ivan Sabol, Anja Barešić
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-04-01
Schriftenreihe:Scientific Reports
Schlagworte:
Head and neck cancer
HPV
miRNome
Methylome
Transcriptome
Integrative analysis
Online-Zugang:https://doi.org/10.1038/s41598-024-59312-z
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