Transcriptional analysis reveals a markedly reduced expression of the voltage-dependent calcium channel α2δ1 subunit in canine prostate cancer compared to benign prostatic hyperplasia

Abstract Background Despite its low incidence, the aggressive nature and high metastatic potential of canine prostate cancer (PC) make it a serious problem in veterinary medicine. However, knowledge of the molecular mechanisms and regulatory networks underlying the development and progression of can...

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Bibliographic Details

Main Authors:	Maciej Zacharski, Maciej Ugorski, Przemysław Prządka, Stanislaw Dzimira, Sonja Škevin, Iwona Sidorkiewicz, Bartłomiej Liszka, Piotr Skrzypczak, Filip Van Nieuwerburgh, Adam Krętowski, Alicja Tomaszek
Format:	Artigo
Language:	Inglês
Published:	BMC 2025-10-01
Series:	BMC Veterinary Research
Subjects:	Canine prostate cancer Benign prostate hyperplasia Gene-expression profiling Calcium channel subunit α2δ1 CACNA2D1
Online Access:	https://doi.org/10.1186/s12917-025-05046-7
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