FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

Abstract Objective Ferritin heavy chain 1 (FTH1) is an important subunit of ferro-storing proteins and is indispensable for iron metabolism. Though it has been extensively studied in numerous organs and diseases, the relationship between FTH1 and osteoarthritis (OA) is unclear. Design Primary murine...

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Bibliografische Detailangaben

Hauptverfasser:	Zhikun Yuan, Lingfeng Yang, Yanhui Li, Xuming Li, Changgui Peng, Jianying Pan, Daozhang Cai
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-04-01
Schriftenreihe:	BMC Musculoskeletal Disorders
Schlagworte:	Osteoarthritis ECM Cartilage Ferroptosis
Online-Zugang:	https://doi.org/10.1186/s12891-024-07411-3
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