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UPF1/SMG7-dependent microRNA-mediated gene regulation

UPF1 mediates the decay of target mRNA in a 3′ untranslated region (UTR)-length-dependent manner. Here the authors reveal that the 3′UTR-length-dependent regulation of UPF1-dependent mRNA decay occurs through EJC-independent but miRNA-dependent regulation.

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Bibliografiske detaljer
Principais autores: Jungyun Park, Jwa-Won Seo, Narae Ahn, Seokju Park, Jungwook Hwang, Jin-Wu Nam
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2019-09-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-019-12123-7
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