Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways

Background: Vincristine (VCR) is used in the clinic as an anti-tumor drug. VCR can cause pulmonary fibrosis (PF), leading to respiratory failure. The transformation of fibroblasts into myofibroblasts may play a key role in PF. The present study attempted to reveal the molecular mechanism of VCR-indu...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Hui Xu, Jingwen Yang, Mengyun Tu, Jie Weng, Mengying Xie, Zhiliang Zhou, Peisen Zhou, Liang Wang, Chan Chen, Zhiyi Wang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2022-05-01
श्रृंखला:	Frontiers in Pharmacology
विषय:	vincristine pulmonary fibrosis fibroblast myofibroblast MAPK
ऑनलाइन पहुंच:	https://www.frontiersin.org/articles/10.3389/fphar.2022.901000/full
टैग:	टैग जोड़ें कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!