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Genetic factors underlying tacrolimus intolerance after liver transplantation

BackgroundTacrolimus (FK506) is the cornerstone of immunosuppression after liver transplantation (LT), however, clinically, switching from FK506 to cyclosporine (SFTC) is common in LT patients with tacrolimus intolerance. The aim of this study was to investigate the genetic risk of patients with tac...

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Principais autores: Yuan Liu, Rui Wang, Peizhen Wen, Wenbin An, Jinxin Zheng, Tao Zhang, Pengshan Zhang, Haoyu Wang, Fan Zou, Hui Pan, Junwei Fan, Zhihai Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-09-01
coleção:Frontiers in Immunology
Assuntos:
CYP3A5
liver transplantation
tacrolimus intolerance
tacrolimus
insulin resistence
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.944442/full
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