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Association of antimicrobial perioperative prophylaxis with cefuroxime plus metronidazole or amoxicillin/clavulanic acid and surgical site infections in colorectal surgery

Abstract Objective To compare intravenous (IV) amoxicillin/clavulanic acid (A/CA) to IV cefuroxime plus metronidazole (C + M) for preventing surgical site infections (SSI) in colorectal surgery. Background Given their spectra that include most Enterobacterales and anaerobes, C + M is commonly recomm...

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Main Authors: Elisavet Stavropoulou, Andrew Atkinson, Marie-Christine Eisenring, Christoph A. Fux, Jonas Marschall, Laurence Senn, Nicolas Troillet
Format: Artigo
Language:Inglês
Published: BMC 2023-09-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Surgical site infection
Antibiotic prophylaxis
Colorectal surgery
Amoxicillin/clavulanic acid
Cefuroxime
Metronidazole
Online Access:https://doi.org/10.1186/s13756-023-01307-y
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