Colon-Specific Delivery of Probenecid Enhances Therapeutic Activity of the Uricosuric Agent Against Rat Colitis
<b>Background/Objectives</b>: Probenecid (PBN) is a uricosuric agent that facilitates the excretion of uric acid and is used to treat gout. Here, a colon-targeted prodrug of PBN was designed to facilitate repositioning as a treatment for inflammatory bowel disease (IBD). <b>Methods</b>: The carboxyl...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI AG
2025-11-01
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| Serier: | Pharmaceutics |
| Fag: | |
| Online adgang: | https://www.mdpi.com/1999-4923/17/11/1454 |
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