Collagen disorder architecture features are associated with clinical, molecular, genetic factors and survival outcomes in colon cancer

Abstract We developed a computational pathology pipeline to extract and analyze collagen disorder architecture (CoDA) features from whole slide images (WSIs) of 2,212 colon cancer (CC) patients across multiple institutions. CoDA features—capturing collagen fragmentation, bundling, anisotropy, densit...

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Bibliografische gegevens

Hoofdauteurs:	Reetoja Nag, Chuheng Chen, Haider Mejbel, Haojia Li, Aya Aqeel, Pingfu Fu, Germán Corredor, Sirvan Khalighi, Tilak Pathak, Mojgan Mokhtari, Michelle Dian Reid, Alyssa M. Krasinskas, Krunal Pandav, Joseph E. Willis, Anant Madabhushi
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Portfolio 2025-08-01
Reeks:	npj Precision Oncology
Online toegang:	https://doi.org/10.1038/s41698-025-01098-y
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