Epigenetic regulation of cocaine intake through dopaminergic control of cholinergic interneurons in male mice
Abstract Substance use disorders are chronic neuropsychiatric conditions influenced by multiple factors, shaping individuals’ vulnerability to addictive drugs like cocaine. Here, we reveal that dopamine D2 receptor mediated inhibition of striatal cholinergic interneurons regulates the motivation for...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-12-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-025-65958-8 |
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