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Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects

Abstract Background Growing evidence has demonstrated that DNA methylation (DNAm) plays an important role in Alzheimer’s disease (AD) and that DNAm differences can be detected in the blood of AD subjects. Most studies have correlated blood DNAm with the clinical diagnosis of AD in living individuals...

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Principais autores: Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-04-01
Serier:Alzheimer’s Research & Therapy
Fag:
DNA methylation
CSF biomarkers
Alzheimer’s disease
Online adgang:https://doi.org/10.1186/s13195-023-01216-7
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