Natural Bred ε²-Phages Have an Improved Host Range and Virulence against Uropathogenic <i>Escherichia coli</i> over Their Ancestor Phages

Alternative treatments for <i>Escherichia coli</i> infections are urgently needed, and phage therapy is a promising option where antibiotics fail, especially for urinary tract infections (UTI). We used wastewater-isolated phages to test their lytic activity against a panel of 47 <i>E. coli</i> strai...

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Principais autores:	Maria Loose, David Sáez Moreno, Michele Mutti, Eva Hitzenhammer, Zehra Visram, David Dippel, Susanne Schertler, Lenka Podpera Tišáková, Johannes Wittmann, Lorenzo Corsini, Florian Wagenlehner
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-11-01
Series:	Antibiotics
Assuntos:	phage therapy phage breeding <i>E. coli</i> urinary tract infections phage training homologous recombination
Acceso en liña:	https://www.mdpi.com/2079-6382/10/11/1337
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