Identification of foam cell like M2 macrophages, AEBP1 biomarkers, and resveratrol as potential therapeutic in MASLD using Ecotyper and WGCNA

Abstract The immune cell landscapes in metabolic dysfunction-associated fatty liver disease (MAFLD) and their clinical relevance have not been explored. We used Ecotyper to identify immune cell states based on gene expression and examined their roles in metabolic dysfunction–associated steatotic liv...

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Detalhes bibliográficos

Principais autores:	Hua Ye, Mengxia Sun, Wenjing Luo, Dahua Chen, Jiacheng Cai, Jia Dong, Liangshun Zhang, Huiwei Liu, Jinyu Kang, Feng Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-08-01
Colecção:	Scientific Reports
Assuntos:	MAFLD Ecotyper Resveratrol Fibroblasts Immune cell landscapes
Acesso em linha:	https://doi.org/10.1038/s41598-025-15191-6
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