Low pH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcγ Receptors: Implications for Measuring Fc Dependent Antibody Functions

Evaluating the biophysical and functional nature of IgG is key to defining correlates of protection in infectious disease, and autoimmunity research cohorts, as well as vaccine efficacy trials. These studies often require small quantities of IgG to be purified from plasma for downstream analysis wit...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Ester Lopez, Nichollas E. Scott, Bruce D. Wines, P. Mark Hogarth, Adam K. Wheatley, Stephen J. Kent, Amy W. Chung
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2019-10-01
سلاسل:	Frontiers in Immunology
الموضوعات:	Fcγ receptors IgG purification protein G melon gel antibody antibody dependent cellular phagocytosis (ADCP)
الوصول للمادة أونلاين:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02415/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!