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Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning.

Physical interactions between cells and the extracellular matrix (ECM) guide directional migration by spatially controlling where cells form focal adhesions (FAs), which in turn regulate the extension of motile processes. Here we show that physical control of directional migration requires the FA sc...

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Váldodahkkit: Julia E Sero, Charles K Thodeti, Akiko Mammoto, Chris Bakal, Sheila Thomas, Donald E Ingber
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2011-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3237434?pdf=render
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