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CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline.

To maintain the integrity of the genome, meiotic DNA double strand breaks (DSBs) need to form by the meiosis-specific nuclease Spo11 and be repaired by homologous recombination. One class of products formed by recombination are crossovers, which are required for proper chromosome segregation in the...

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Autores principales: Benjamin Alleva, Sean Clausen, Emily Koury, Adam Hefel, Sarit Smolikove
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2019-11-01
Colección:PLoS Genetics
Acceso en línea:https://doi.org/10.1371/journal.pgen.1008486
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