Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

Abstract Background Intravenous fluids, an essential component of sepsis resuscitation, may paradoxically worsen outcomes by exacerbating endothelial injury. Preclinical models suggest that fluid resuscitation degrades the endothelial glycocalyx, a heparan sulfate-enriched structure necessary for va...

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Manylion Llyfryddiaeth

Prif Awduron:	Joseph A. Hippensteel, Ryo Uchimido, Patrick D. Tyler, Ryan C. Burke, Xiaorui Han, Fuming Zhang, Sarah A. McMurtry, James F. Colbert, Christopher J. Lindsell, Derek C. Angus, John A. Kellum, Donald M. Yealy, Robert J. Linhardt, Nathan I. Shapiro, Eric P. Schmidt
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2019-07-01
Cyfres:	Critical Care
Pynciau:	Sepsis Multiple organ failure Endothelial glycocalyx Fluid resuscitation
Mynediad Ar-lein:	http://link.springer.com/article/10.1186/s13054-019-2534-2
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!