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Identification of a TGF-β1 homologue in the large yellow croaker (Larimichthys crocea) revealed its role in regulation of immune response

Mammalian TGF-β1 plays a crucial role in maintaining immune tolerance and inhibiting autoimmunity. Although several TGF-β1 homologues have been identified in teleosts, their immunosuppressive functions remain unclear. Herein, we identified and characterized LcTGF-β1, a TGF-β1 homologue from the larg...

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Principais autores: Xiaofeng Li, Pengfei Mu, Yan Teng, Xiaomeng Li, Yinanzi Wu, Xinhua Chen
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co. Ltd. 2022-02-01
coleção:Water Biology and Security
Assuntos:
Large yellow croaker
TGF-β1
Monocytes/macrophage
T cells
Immunoregulation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2772735122000026
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