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3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer

Abstract Objectives Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype with limited treatment options. Unlike other breast cancer subtypes, the scarcity of specific therapies and greater frequencies of distant metastases contribute to its aggressiveness. We aimed to fi...

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Principais autores: Pere Llinàs-Arias, Miquel Ensenyat-Méndez, Javier I. J. Orozco, Sandra Íñiguez-Muñoz, Betsy Valdez, Chuan Wang, Anja Mezger, Eunkyoung Choi, Yan Zhou Tran, Liqun Yao, Franziska Bonath, Remi-André Olsen, Mattias Ormestad, Manel Esteller, Mathieu Lupien, Diego M. Marzese
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:BMC Genomic Data
Fag:
Epigenetic profiling
Chromatin accessibility
Long-range interactions
RNA levels
ATAC-seq
Hi-C
Online adgang:https://doi.org/10.1186/s12863-023-01166-x
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