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Characterization of a Conjugative Multidrug Resistance IncP-2 Megaplasmid, pPAG5, from a Clinical Pseudomonas aeruginosa Isolate

ABSTRACT The spread of resistance genes via horizontal plasmid transfer plays a significant role in the formation of multidrug-resistant (MDR) Pseudomonas aeruginosa strains. Here, we identified a megaplasmid (ca. 513 kb), designated pPAG5, which was recovered from a clinical multidrug-resistant P....

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Principais autores: Meng Li, Congcong Guan, Gaoyu Song, Xiaoxi Gao, Weina Yang, Tietao Wang, Yani Zhang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2022-02-01
Serier:Microbiology Spectrum
Fag:
Pseudomonas aeruginosa
conjugative plasmid
multidrug resistance
IncP-2 plasmid
plasmid evolution
Online adgang:https://journals.asm.org/doi/10.1128/spectrum.01992-21
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