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Loss of IGFBP-6 promotes monocyte-driven atherogenesis in periodontal disease

Abstract Periodontitis has been associated with an increased risk of atherosclerosis, potentially through altered systemic monocyte and macrophage function. We aimed to identify a differentially expressed protein in naïve monocytes from individuals with periodontitis compared to controls and investi...

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Bibliographic Details
Main Authors: Dáire Shanahan, Georgios Kremastiotis, Kerry Wadey, Claudine Hodgson, Joon Seong, Nicola West, Angela H. Nobbs, Jason Johnson, Sarah George
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2026-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-026-47023-6
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