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Evaluation of Surrogate Endpoints Using Information-Theoretic Measure of Association Based on Havrda and Charvat Entropy

Surrogate endpoints have been used to assess the efficacy of a treatment and can potentially reduce the duration and/or number of required patients for clinical trials. Using information theory, Alonso et al. (2007) proposed a unified framework based on Shannon entropy, a new definition of surrogacy...

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Autors principals: María del Carmen Pardo, Qian Zhao, Hua Jin, Ying Lu
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-01-01
Col·lecció:Mathematics
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Accés en línia:https://www.mdpi.com/2227-7390/10/3/465
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